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Current Projects  |  Past ContributionsResearch Publications


Year Recipient Amount
2010 University of Florida College of Dentistry   
University of Florida College of Denttistry for Oral Cancer Research - Commited to a 5 Year Fellowship 
 $35,000
$175,000
2009 University of Florida College of Dentistry
University of Florida College of Medicine   
$25,000
$15,000
2008 University of Florida College of Medicine
University of Florida College of Dentistry   
$17,000
$12,000
2007 University of Florida College of Dentistry
$28,000
2006  University of Florida College of Medicine
$100,000
2005 University of Florida College of Medicine
Department of Otolaryngology
$30,000
2003 University of Florida College of Medicine
Department of Otolaryngology
$20,000
2002 University of Florida College of Medicine
Department of Otolaryngology
$10,000
2001 University of Florida College of Medicine
Department of Otolaryngology
$1,250





2010

The Foundation committed to provide the University of Florida College of Dentistry with $175,000 over 5 years.  These funds will be used to support a Fellowship dedicated to genetic research in oral cancer detection and therapy.

2009
We donated $15,000 to the UF College of Medicine towards the Andrew J. Semesco Fund for Oral, Head, and Neck Cancer Research endowment and $25,000 to the UF College of Dentistry to fund a project investigating early detection of Oral Cancer using genetic markers. The information gathered from this study is aimed at developing a simple test to find oral cancer much earlier than current means.

2008
Our foundation increased the principal of the endowment by $17,000. This was eligible for 50% matching from the state. $12,000 went directly to fund a project at the University of Florida college of Dentistry to explore a loinke between Human Papillomavirus (HPV) and oral cancers such as Squamous Cell Carcinoma.  The funds covered laboratory materials, costs, and equipment.  

2007
$25,000 was donated to the University of Florida College of Dentistry to fund research in novel gene therapy of oral, head and neck cancers. $3,000 was donated to the UF college of dentistry for a study to evaluate the consistency of dental treatment and management protocols among radiation oncologist and dentists for oral, head and neck patience.

2006
Our foundation established an endowed fund of $100,000 at the University of Florida College of Medicine. This is an endowed fund of which the interest is used every year for research efforts at the new, state of the art UF Shands Cancer and Genetic Research Center. The fund is eligible for state fund matching at a 50% level.

2005
$30,000 was donated to the University of Florida College of Medicine Department of Otolaryngology for the purpose of cancer research. The project funded will achieve three main objectives:
  1. Analyze DNA content in archival dysplastic leukoplakia using image cytometry. Image cytometry will be performed at the University of Florida Diagnostic Referral Laboratories. This laboratory will analyze specimens on a fee-for-service basis.
  2. Correlate DNA content with disease progression. Survival curves as a function of DNA content (diploid, aneuploid, and tetraploid) will be constructed according to Kaplan-Meier with the end points being development of squamous cell carcinoma and disease-free survival. A log-rank test will be used to assess the prognostic value of DNA content in relation to disease-free survival.
  3. Analyze expression of select genes in leukoplakia. Potential prognostic markers will be analyzed by real-time PCR and immunohistochemistry and expression of these genes will be correlated with clinical outcome.
2003
2003 proved to be a very successful year for the Andrew J. Semesco Foundation, Inc. Due to our increasing public support and excellent volunteers we were able to make a research contribution of $20,000 to the University of Florida College of Medicine Department of Otolaryngology research laboratory.

2002
$10,000 was donated to the University of Florida Department of Otolaryngology research laboratory. The type of research that will be done in this laboratory is called microarray technology. Microarray technology is an extremely powerful technique that allows one to develop a profile of genes that are expressed in a tumor. It is predicted that patterns of gene expression within tumors can be used to predict the clinical behavior (sensitivity to treatment, metastasis, future recurrence) of an individual’s cancer. Funds will therefore be used to begin to construct gene expression databases that will ultimately be used to predict tumor behavior

2001
Due to our generous donors we were able to make a $1,250.00 contribution to the University of Florida Department of Otolaryngology research laboratory for the calendar year of 2001.

Prevention
$3,000 was donated to the University of Florida College of Dentistry to fund a joint project with the University of Florida to increase the awareness of oral cancer among illiterate populations. This grant is sufficient to fund the whole project.
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